Actiq

Actiq

ACTIQ is used for the management of breakthrough pain in cancer patients 16 years of age and older. Patients must be tolerant to around-the-clock opioid therapy for their underlying persistent cancer pain.

About Actiq

Actiq by Cephalon, is a solid formulation of fentanyl citrate on a plastic stick that dissolves slowly in the mouth for absorption across the buccal mucosa. Generically Actiq is a form of oral transmucosal fentanyl citrate (OTFC). In the UK, Fentanyl is a Class A drug under the Misuse of Drugs Act 1971. In the Netherlands, Fentanyl is a List I substance of the Opium Law. In the US, Fentanyl is a Schedule II controlled substance per the Controlled Substance Act. Other pharmaceutical preparations consisting of fentanyl are Durogesic and Duragesic (72 hour continuous-release fentanyl patches) and Fentora, a rapidly dissolving fentanyl lozenge which, like Actiq, is administered transmucosally over the buccal mucosa. OTFC is absorbed much as nicotine is absorbed when dipping tobacco is placed in one's mouth between the gum and cheek. An Actiq lozenge contains 2 grams of sugar (8 calories). The status of a sugar-free version, called Actiq-SF, is unclear.

Contributions by Gzuckier, Crohnie, and SlimNm.