Biotechnology (sometimes shortened to 'biotech') is generally accepted as the use of living systems and organisms to develop or make useful products. For thousands of years, humankind has used biotechnology in agriculture, food production and medicine. The term itself is largely believed to have been coined in 1919 by Hungarian engineer Karl Ereky. In the late 20th and early 21st century, biotechnology has expanded to include new and diverse sciences such as genomics, recombinant gene technologies, applied immunology, and development of pharmaceutical therapies and diganostic tests.. The concept of 'biotech' or 'biotechnology' encompasses a wide range of procedures (and history) for modifying living organisms according to human purposes going back to domestication of animals, cultivation of plants, and 'improvements' to these through breeding programs that employ artificial selection and hybridization.