Buspirone trade name Buspar is an anxiolytic psychoactive drug of the azapirone chemical class and is primarily used to treat generalized anxiety disorder (GAD). In 1986, Bristol-Myers Squibb (BMS) gained Food and Drug Administration (FDA) approval for buspirone in the treatment of GAD. The BMS patent placed on buspirone expired in 2001 and buspirone is now available as a generic drug. Although not approved for this indication, studies have shown buspirone to be an effective augmentation agent alongside treatment with SSRIs for clinical depression. Most common adverse effects: Buspirone has the following contraindications: Buspirone has been shown in vitro to be metabolized by CYP3A4. This finding is consistent with the...'