Foldit

Foldit

About Foldit

Foldit is an online puzzle video game about protein folding. The game is part of an experimental research project, and is developed by the University of Washington's Center for Game Science in collaboration with the UW Department of Biochemistry. The objective of the game is to fold the structure of selected proteins to the best of the player's ability, using various tools provided within the game. The highest scoring solutions are analysed by researchers, who determine whether or not there is a native structural configuration (or native state) that can be applied to the relevant proteins, in the real world. Scientists can then use such solutions to solve real-world problems, by targeting and eradicating diseases, and creating biological innovations. David Baker, a protein research scientist at the University of Washington, is responsible for beginning the Foldit project. Prior to the project's commencement, Baker and his laboratory co-workers relied upon another research project, Rosetta, to predict the native structures of various proteins, using special computer protein structure prediction algorithms. The project was eventually extended to utilize the processing power of

Contributions by Tristanlbailey, Gurchzilla, and Tripodian.