Independence is the fourth-largest city in the U.S. state of Missouri. Most of Independence lies within Jackson County, of which it is the county seat, although a small portion of the city lies in Clay County. Independence is a satellite city of Kansas City, Missouri, and is part of the Kansas City metropolitan area. In 2010, Independence had a total population of 116,830 Independence is known as the 'Queen City of the Trails' because it was a point of departure of the California, Oregon and Santa Fe Trails. Independence is also noted as the hometown of President Harry S. Truman; the Truman Presidential Library and Museum is located in the city, and Truman and First Lady Bess Truman are buried here.