Lauren Elizabeth 'Laurie' Metcalf (born June 16, 1955) is an American actress. She is perhaps most widely known for her performance as Jackie Harris on the ABC sitcom Roseanne and has also had series television roles as Carolyn Bigsby on Desperate Housewives and Mary Cooper on The Big Bang Theory. Her motion picture roles include the voice of Mrs. Davis in the Toy Story film series and the character Debbie Loomis/Debbie Salt in Scream 2, as well as roles in such critically acclaimed films as Making Mr. Right, JFK, and Mistress. Metcalf frequently works in Chicago theater, where she is well known for her performance in the 1983 revival of Lanford Wilson's play Balm in Gilead. She has also appeared in commercials for Plan USA, a humanitarian organization which helps children in need around the world.