Necrotizing fasciitis or NF, commonly known as flesh-eating disease or flesh-eating bacteria syndrome, is a rare infection of the deeper layers of skin and subcutaneous tissues, easily spreading across the fascial plane within the subcutaneous tissue. Necrotizing fasciitis is quickly progressing, having greater risk of developing in the immunocompromised due to conditions like Diabetes, Cancer, etc. It is a severe disease of sudden onset and is usually treated immediately with high doses of intravenous antibiotics. Type I describes a polymicrobial infection, whereas Type II describes a monomicrobial infection. Many types of bacteria can cause necrotizing fasciitis (e.g., Group A streptococcus (Streptococcus pyogenes), Staphylococcus aureus, Clostridium perfringens, Bacteroides fragilis, Aeromonas hydrophila). Such infections are more likely to occur in people with compromised immune systems.
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