Palindromic Rheumatism (PR) consists of sudden and rapidly developing attacks of arthritis. There is acute pain, redness, swelling, and disability of one (usually) or multiple joints. The interval between recurrent attacks is extremely variable and how long the attack lasts is also variable. There is no joint damage after attacks. Due to the symptoms of Palindromic arthiritis and the nature of the attacks, diagnosis can be difficult or take time. The symptoms can be similar to many other forms of arthritis or other auto-immune diseases. It is often a case of eliminating the other conditions before getting the correct diagnosis due to there being no specific test for PR diagnosis. No single test can confirm a diagnosis. A doctor may make a diagnosis based on medical history and signs and symptoms. Palindromic rheumatism must be distinguished from acute gouty arthritis and an atypical, acute onset of rheumatoid arthritis (RA).
Contributions by Iprs, Arcadian, and Cuaxdon.