Texas A&M University (often referred to as A&M or TAMU) is a coeducational public research university located in College Station, Texas, United States. It is the flagship institution of the Texas A&M University System, the sixth-largest university in the United States and the largest university in Texas. Texas A&M's designation as a land, sea, and space grant institution reflects a broad range of research with ongoing projects funded by agencies such as the National Aeronautics and Space Administration (NASA), the National Institutes of Health, the National Science Foundation, and the Office of Naval Research. The school ranks in the top 20 American research institutes in terms of funding and has made notable contributions to such fields as animal cloning and petroleum engineering. The first public institution of higher education in Texas, the school opened on October 4, 1876 as the Agricultural and Mechanical College of Texas.