Warkany syndrome

Warkany syndrome

About Warkany syndrome

Warkany syndrome 1 is an X-chromosome linked recessive genetic condition originally described by Warkany in 1961 as part of an article on intrauterine growth retardation. The family history was consistent with X-linked recessive inheritance of intrauterine growth retardation and small head size, but these features are not unique to this condition and no linkage to a specific gene was ever established. In fact, the condition appears to have been abandoned, given that the OMIM number (308400) assigned to it and listed in a review article on X-linked mental retardation has been removed from the OMIM database. Furthermore, this condition is no longer mentioned in a more recent review of X-linked mental retardation. Warkany syndrome 2, or simply 'Warkany syndrome', is used by some authors when referring to chromosome 8 trisomy syndrome (Trisomy 8).